Transglutaminase 2 ist ein Gen, das durch das Symbol TGM2 kodiert wird. Es ist auch bekannt als: Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; TG(C); Transglutaminase H; TGase H; Transglutaminase-2; TGase-2; TGM2. Transglutaminase 2 hat eine Masse von 77.33kDa und eine Aminosäurelänge von 687.
Wir bieten 3 Transglutaminase 2proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Catalyzes the cross-linking of proteins, such as WDR54, and the conjugation of polyamines to proteins.
Entrez Zusammenfassung
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Sequenzähnlichkeiten
Belongs to the transglutaminase superfamily. Transglutaminase family.
