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Anti-SOX4 Antikörper [PCRP-SOX4-1D6] (A277796)

Monoklonal [PCRP-SOX4-1D6] Maus Antikörper gegen SOX4 für IP, Flow Cytometry, IF, WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-SOX4 Antibody [PCRP-SOX4-1D6]
Beschreibung
Mouse monoclonal [PCRP-SOX4-1D6] antibody to SOX4.
Spezifität
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF-β-induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival invitro and for primary tumor growth and metastasis invivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.
Anwendungen
IP, Flow Cytometry, IF, WB, IHC-P
Verdünnungen
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Kreuzreaktivität
This antibody is predicted to cross react with Xenopus and Chicken.
Immunogen
Recombinant fragment, around amino acids 45-130, of human SOX4 protein .The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PCRP-SOX4-1D6
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
47 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-SOX4 Antibody [PCRP-SOX4-1D6] - BSA and Azide free (A278384).
Synonyme
Ecotropic viral integration site 16, EVI 16, EVI16, SOX4_HUMAN, SRY (sex determining region Y) box 4, SRY box containing gene 4, SRY related HMG box gene 4, Transcription factor SOX-4
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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