Synthetik Nanodisc Human CCR8 Protein (A318461)

Name: Synthetic Nanodisc Human CCR8 Protein
Brand: Antibodies.com
SKU: A318461
Price: 1300.0 USD
Availability: InStock

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$1,300

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Versandkosten

$40

Vorlaufzeit

Lieferung in 7-8 Werktagen

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Produktdetails

Produktname

Synthetic Nanodisc Human CCR8 Protein

Beschreibung

Synthetic nanodiscs offer a stable and biologically relevant environment that closely mimics cell membranes and enables full-length transmembrane human CCR8 protein to be purified and analysed in vitro.

Anwendungen

Western Blot, ELISA, SDS-PAGE

Ausdruckssystem

HEK293 cells

Natur

Synthetic

Spezies

Human

Proteinlänge

Full length protein.

Molekulargewicht

Full length human CCR8 protein has a MW of 40.7 kDa.

Konjugat

Unconjugated

Produktform

Lyophilized

Konzentration

Reconstitution dependent.

Formulierung

Lyophilized from nanodisc solubilization buffer (20mM Tris-HCl, 150mM NaCl, pH 8.0). Normally 5%–8% Trehalose is added as a protectant before lyophilization.

Lagerung

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonyme

C C chemokine receptor type 8, C C CKR 8, C C motif chemokine receptor 8, C-C chemokine receptor type 8, C-C CKR-8, CC chemokine receptor 8, CC chemokine receptor CHEMR1, CC chemokine receptor type 8, CC CKR 8, CC-CKR-8, CCR 8, CCR-8, CCR8 protein, CCR8-L, CCR8_HUMAN, CDw198, CDw198 antigen, Chemokine (C C motif) receptor 8, Chemokine (C C) receptor 8, Chemokine (C C) receptor like 2, Chemokine (CC motif) receptor 8, Chemokine (CC) receptor 8, Chemokine (CC) receptor like 1, Chemokine (CC) receptor like 2, Chemokine C C motif receptor 8, Chemokine C C receptor 8, Chemokine CC motif receptor 8, Chemokine CC receptor 8, Chemokine receptor 8, Chemokine receptor like 1, Chemokine receptor-like 1, CKR L1, CKR-L1, CKRL 1, CKRL1, CMKBR 8, CMKBR L2, CMKBR8, CMKBRL 2, CMKBRL2, CY 6, CY6, GPR CY6, GPR-CY6, GPRCY6, MGC123958, MGC123959, MGC129966, MGC129973, TER 1, TER1

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (4)

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Figure 1: Synthetic Nanodisc Human CCR8 Protein (A318461)

ELISA plates were pre-coated with Synthetic Nanodisc Human CCR8 Protein (A318461) (0.2 µg/well). Serial diluted Anti-CCR8 Humanized Antibody [BMS 986340] - Azide free (A318852) solutions were added, washed, and incubated with secondary antibody before ELISA reading. From this data, the EC50 for Anti-CCR8 Monoclonal Antibody binding with CCR8-Nanodisc is 12.07 µg/ml.

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Figure 2: Western Blot - Synthetic Nanodisc Human CCR8 Protein (A318461)

Western blot analysis of Synthetic Nanodisc Human CCR8 Protein (A318461) with Anti-CCR8 Humanized Antibody [BMS 986340] - Azide free (A318852) at 1 µg/ml, followed by Goat Anti-Human IgG Antibody (HRP) at 1:5,000 dilution.

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Figure 3: Synthetic Nanodisc Human CCR8 Protein (A318461)

Synthetic Nanodisc Human CCR8 Protein (A318461) can bind Anti-CCR8 Humanized Antibody [BMS 986340] - Azide free (A318852) with an affinity constant of 1.408 nM as determined in a SPR assay.

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Figure 4: Synthetic Nanodisc Human CCR8 Protein (A318461)

Diagram showing how synthetic nanodiscs containing full-length multi-pass transmembrane proteins in a phospholipid bilayer are generated from native cell membranes.