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Anti-TRBP Antikörper [PCRP-TARBP2-1E5] (A250079)

Monoklonal [PCRP-TARBP2-1E5] Maus Antikörper gegen TRBP für Flow Cytometry, IF und WB.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-TRBP Antibody [PCRP-TARBP2-1E5]
Beschreibung
Mouse monoclonal [PCRP-TARBP2-1E5] antibody to TRBP.
Spezifität
TRBP2, also known as TARBP2 (trans-activation-responsive (HIV-1) RNA binding protein 2), TRBP1 or TRBP, is a nuclear protein that contains three DRBM (double-stranded RNA-binding) domains. TRBP binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. The third DRBM motif in the C-terminus of human TRBP2 can interact with and inhibit PKR activity, thereby increasing HIV-1 long terminal repeat (LTR) expression. In addition, TRBP2 functions as a component of a Dicer-containing complex and associates with the catalytic subunit of the RNA-induced silencing complex (RISC), namely eIF2C2. TRBP2 is essential for Dicer stability and the proper assembly of RISC. This suggests that TRBP2, in association with Dicer, plays an important role in the processing of miRNAs (microRNAs).
Anwendungen
Flow Cytometry, IF, WB
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant full-length human TARBP2 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PCRP-TARBP2-1E5
Isotyp
IgG2a
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
45 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-TRBP Antibody [PCRP-TARBP2-1E5] - BSA and Azide free (A253259).
Synonyme
LOQS, Prbp, RISC loading complex subunit TARBP2, RISC-loading complex subunit tarbp2, TAR (HIV 1) RNA binding protein 2, TAR (HIV) RNA binding protein 2, TAR (HIV) RNA-binding protein TRBP1, TAR RNA Binding Protein 2, TAR RNA-binding protein 2, tarbp2, TARBP2 RISC loading complex RNA binding subunit, Trans-activation-responsive RNA-binding protein, TRBP1, TRBP2, TRBP2_HUMAN
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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