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Anti-UBE2B Antikörper [PCRP-UBE2B-1C7] (A250264)

Monoklonal [PCRP-UBE2B-1C7] Maus Antikörper gegen UBE2B für Flow Cytometry und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-UBE2B Antibody [PCRP-UBE2B-1C7]
Beschreibung
Mouse monoclonal [PCRP-UBE2B-1C7] antibody to UBE2B.
Spezifität
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (ubiquitin-conjugating enzyme E2 A) and UBE2B (ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to post replication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.
Anwendungen
Flow Cytometry, IF
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reaktivität
Human
Kreuzreaktivität
This antibody is predicted to cross react with Mouse, Rat, Xenopus, and Zebrafish.
Immunogen
Recombinant full-length human UBE2B protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PCRP-UBE2B-1C7
Isotyp
IgG2b
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
17 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-UBE2B Antibody [PCRP-UBE2B-1C7] - BSA and Azide free (A253444).
Synonyme
E2 17kDa, E2 protein, hHR6B, HR6B, RAD6 homolog B, RAD6B, UBC2, UBE2B_HUMAN, Ubiquitin carrier protein B, Ubiquitin conjugating enzyme E2 B, Ubiquitin conjugating enzyme E2B, Ubiquitin conjugating enzyme E2B (RAD6 homolog), Ubiquitin protein ligase B, Ubiquitin-conjugating enzyme E2 17 kDa, Ubiquitin-conjugating enzyme E2 B, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-protein ligase B
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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