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Anti-Ubiquitin Antikörper [UBB/1748] (A253441)

Monoklonal [UBB/1748] Maus Antikörper gegen Ubiquitin für Flow Cytometry, WB, IF und IHC-P.

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Vorlaufzeit
Lieferung in 4-6 Werktagen
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+1 (314) 370-6046
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Empfohlene Produkte für Anti-Ubiquitin Antikörper

Produktname
Anti-Ubiquitin Antibody [UBB/1748] - BSA and Azide free
Beschreibung
Mouse monoclonal [UBB/1748] antibody to Ubiquitin.
Spezifität
Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimers disease etc.
Anwendungen
Flow Cytometry, WB, IF, IHC-P
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 1-119, of human Ubiquitin protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
UBB/1748
Isotyp
IgG2c
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
9 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Ubiquitin Antibody [UBB/1748] (A250261).
Synonyme
Epididymis secretory protein Li 50, FLJ25987, HEL S 50, MGC8385, Polyubiquitin B, RPS 27A, RPS27A, UBA 52, UBA 80, UBA52, UBA80, UBB, UBB_HUMAN, UBC, UBCEP 1, UBCEP 2, UBCEP1, UBCEP2, Ubiquitin B, UBIQ_HUMAN
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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