Anti-AHSG Anticorps [AHSG/3748] (A277583)

Name: Anti-AHSG Antibody [AHSG/3748]
Brand: Antibodies.com
SKU: A277583
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [AHSG/3748] de souris contre AHSG pour IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

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Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

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Mots clés :

Anticorps Monospécifique

Spécifications

Nom du produit

Anti-AHSG Antibody [AHSG/3748]

Description du produit

Mouse monoclonal [AHSG/3748] antibody to AHSG.

Spécificité

Fetuin (also designated Î±2-z-globulin or Î±2-HS-glycoprotein) is a secreted plasma protein that is expressed in hepatocytes, monocyte/macrophages and in bone and is downregulated during injury and inflammation. Fetuin preferentially binds to and carries calcium and barium ions in the blood, where it is thought to mediate serum calcium homeostasis and mineralization, and to potentially participate in the transport of bioactive molecules. Additionally, fetuin has been shown to function as an acute phase anti-inflammatory mediator that is critical to regulating the innate immune response following tissue injury. During inflammation, circulating fetuin levels substantially decrease as fetuin becomes associated with the membranes of macrophages. This membrane associated form of fetuin acts as an opsonic participant by potentiating the entry of cationic small molecules into the activated macro-phage, which in turn facilitates macrophage-deactivating mechanisms. Biologically active fetuin is derived from a precursor protein that is cleaved at the aminoterminus to generate two chains held together by a single disulfide bond.

Applications

IHC-P

Recommander des dilutions

IHC-P: 1-2 µg/ml

Reactivité

Human

Immunogène

Recombinant fragment corresponding to human AHSG protein. The exact sequence is proprietary.

Hôte

Mouse

Clonalité

Monoclonal

Clone

AHSG/3748

Isotype

IgG1

Chaînes légères

kappa

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Masse moléculaire

59 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-AHSG Antibody [AHSG/3748] - BSA and Azide free (A278171).

Synonymes

59 kDa bone sialic acid-containing protein, A2HS, Aa2-066, AHS, Ahsg alpha-2-HS-glycoprotein, Alpha 2 HS Glycoprotein, Alpha 2 Z globulin, Alpha-2-HS-glycoprotein, Alpha-2-HS-glycoprotein chain B, Alpha-2-Z-globulin, Asialofetuin, Ba alpha 2 glycoprotein, Ba-alpha-2-glycoprotein, BSP, Countertrypin, Fetua, FETUA_HUMAN, Fetuin , mouse, homolog of, Fetuin A, Fetuin-A, Glycoprotein PP63, HSGA, pp63

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (3)

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Figure 1: Immunohistochemistry - Anti-AHSG Antibody [AHSG/3748] (A277583)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human placenta tissue using Anti-AHSG Antibody [AHSG/3748] at 2µg/ml. Inset: PBS instead of the primary antibody. Secondary antibody negative control.

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Figure 2: SDS-PAGE - Anti-AHSG Antibody [AHSG/3748] (A277583)

SDS-PAGE analysis of Anti-AHSG Antibody [AHSG/3748] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 3: Anti-AHSG Antibody [AHSG/3748] (A277583)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-AHSG Antibody [AHSG/3748]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.