Anti-BCL11A Anticorps [PCRP-BCL11A-1G10] (A277750)

Anticorps monoclonal [PCRP-BCL11A-1G10] de souris contre BCL11A pour ELISA, WB, IP, Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-BCL11A Antibody [PCRP-BCL11A-1G10]
Description du produit
Mouse monoclonal [PCRP-BCL11A-1G10] antibody to BCL11A.
Spécificité
Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
Applications
ELISA, WB, IP, Flow Cytometry, IF
Recommander des dilutions
WB: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivité
Human
Réactivité croisée
This antibody is predicted to cross react with Mouse and Rat.
Immunogène
Recombinant full-length human BCLL1A protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-BCL11A-1G10
Isotype
IgG2a
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
91.2 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-BCL11A Antibody [PCRP-BCL11A-1G10] - BSA and Azide free (A278338).
Synonymes
2810047E18Rik, B cell CLL/lymphoma 11A (zinc finger protein), B cell CLL/lymphoma 11A (zinc finger protein) isoform 2, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BC11A_HUMAN, BCL-11A, BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1, BCL11A L, BCL11A S, BCL11A XL, BCL11a-M, BCL11AL, BCL11AS, BCL11AXL, C2H2 type zinc finger protein, COUP TF interacting protein 1, COUP-TF-interacting protein 1, Ctip1, CTIP1, mouse, homolog of, D930021L15Rik, Ecotropic viral integration site 9, Ecotropic viral integration site 9 homolog, Ecotropic viral integration site 9 protein, Ecotropic viral integration site 9 protein homolog, EVI-9, Evi9, Evi9, mouse, homolog of, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, mKIAA1809, OTTHUMP00000159788, OTTHUMP00000159789, OTTHUMP00000201250, OTTHUMP00000202084, Zinc finger protein 856, ZNF856
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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