Recombinant Anti-beta 2 Microglobulin Anticorps [B2M/1857R] (A249754)

Anticorps monoclonal [B2M/1857R] de lapin contre beta 2 Microglobulin pour ELISA, Flow Cytometry et WB.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-beta 2 Microglobulin Antibody [B2M/1857R]
Description du produit
Recombinant rabbit monoclonal [B2M/1857R] antibody to beta 2 Microglobulin.
Spécificité
This antibody recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alphaheavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alphaheavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alphaheavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Applications
ELISA, Flow Cytometry, WB
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivité
Human, Non-Human Primates
Immunogène
Recombinant full-length human B2M protein.
Hôte
Rabbit
Clonalité
Monoclonal
Clone
B2M/1857R
Isotype
IgG
Conjuguer

Unconjugated

Purification
Protein A chromatography.
Concentration
200 µg/ml
Masse moléculaire
12 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-beta 2 Microglobulin Antibody [B2M/1857R] - BSA and Azide free (A252934).
Synonymes
B2M, B2MG_HUMAN, Beta 2 microglobin, Beta 2 microglobulin precursor , Beta chain of mhc class 1 proteins , Beta chain of MHC class I molecules, Beta-2-microglobulin form pI 5.3, CDABP0092, Hdcma22p, IMD43
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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