Anti-CD11b Anticorps [ICRF44] (A280695)

Anti-CD11b Antibody [ICRF44] - BSA and Azide free

Mouse monoclonal [ICRF44] antibody to CD11b.

This antibody recognises the human CD11b cell surface glycoprotein, a 165 kDa molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes. Mouse anti Human CD11b antibody, clone ICRF44 has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.

IHC-Fr, Flow Cytometry, IP, Functional Assays

Flow Cytometry: 1:10 - 1:100, IHC-Fr 1: 1:100 - 1:1,000, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Human, Cynomolgus monkey, Baboon, Rhesus Monkey

This antibody does not cross react with Cat

Rheumatoid synovial cells and human monocytes.

Mouse

Monoclonal

ICRF44

IgG1

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD11b antibody, clone ICRF44 recognizes the human CD11b cell surface glycoprotein, a 165 kDa molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes.Mouse anti Human CD11b antibody, clone ICRF44 has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.

antigen CD11b (p170), Antigen CD11b p170, CD11 antigen like family member B, CD11 antigen-like family member B, CD11b/CD18, CD49d, Cell surface glycoprotein MAC-1 subunit alpha, Complement component 3 receptor 3 subunit, Complement Component Receptor 3 Alpha, Complement receptor type 3, alpha subunit, CR 3 alpha chain, CR 3 alpha chain (CR3A), CR-3 alpha chain, CR3, CR3A, F730045J24Rik, Integrin Alpha M, Integrin alpha M chain, Integrin alpha-M, Integrin beta 2 alpha subunit, Integrin subunit alpha M, integrin, alpha M (complement component 3 receptor 3 subunit), ITAM_HUMAN, ITGAM, Leukocyte adhesion receptor MO1, Ly-40, MAC 1, Mac-1a, MAC1, Mac1, alpha subunit, MAC1A, Macrophage antigen alpha polypeptide, MGC117044, Mo1, alpha subunit, MO1A, Neutrophil adherence receptor, Neutrophil adherence receptor alpha M subunit, SLEB6