This antibody recognises the human CD89 cell surface antigen, a 50-75 kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R).CD89 is expressed by peripheral blood monocytes and neutrophils.MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
Applications
Flow Cytometry
Recommander des dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells or 100µl whole blood
Reactivité
Human
Immunogène
Recombinant soluble human Fc alpha R.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MIP8a
Isotype
IgG1
Conjuguer
PE
Excitation: 565nm, Emission: 578nm
Concentration
Reconstitution dependent.
Forme du produit
Lyophilized
Reconstitution
Reconstitute with 1 ml of distilled water.
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Stockage
Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Mouse anti Human CD89 antibody, clone MIP8a recognizes the human CD89 cell surface antigen, a 50-75 kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R).CD89 is expressed by peripheral blood monocytes and neutrophils.MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
Synonymes
Fc alpha receptor, Fc fragment of IgA, receptor for, FCAR, FCAR_HUMAN, IgA Fc receptor, Immunoglobulin alpha Fc receptor