Anti-Cyclin D1 Anticorps [SPM587] (PE) (A251192)

Anticorps monoclonal [SPM587] de souris contre Cyclin D1 (PE) pour Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Cyclin D1 Antibody [SPM587] (PE)
Description du produit
Mouse monoclonal [SPM587] antibody to Cyclin D1 (PE).
Spécificité
This antibody recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Applications
Flow Cytometry, IF
Recommander des dilutions
Flow Cytometry: 5-10 µl / million cells, IF: 1:50-1:100
Reactivité
Human, Monkey, Mouse, Rat
Immunogène
Recombinant full-length human Cyclin D1 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
SPM587
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

PE

Excitation: 565nm, Emission: 578nm

Purification
Protein A/G chromatography.
Concentration
100 µg/ml
Masse moléculaire
36 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Store at 4-8°C. Antibody is stable for 24 months.
Synonymes
AI327039, B cell CLL/lymphoma 1, B cell leukemia 1, B cell lymphoma 1 protein, B-cell lymphoma 1 protein, BCL 1, BCL-1, BCL-1 oncogene, BCL1, BCL1 oncogene, ccnd1, CCND1/FSTL3 fusion gene, included, CCND1/IGHG1 fusion gene, included, CCND1/IGLC1 fusion gene, included, CCND1/PTH fusion gene, included, CCND1_HUMAN, cD1, Cyl 1, D11S287E, G1/S specific cyclin D1, G1/S-specific cyclin-D1, Parathyroid adenomatosis 1, PRAD1, PRAD1 oncogene, U21B31
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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