Anti-Decorin Anticorps [DCN/6289] (A278223)

Name: Anti-Decorin Antibody [DCN/6289] - BSA and Azide free
Brand: Antibodies.com
SKU: A278223
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [DCN/6289] de souris contre Decorin pour Flow Cytometry, IF, WB et IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Spécifications

Nom du produit

Anti-Decorin Antibody [DCN/6289] - BSA and Azide free

Description du produit

Mouse monoclonal [DCN/6289] antibody to Decorin.

Spécificité

Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGFÎ² and is a direct or indirect negative modulator of TGFÎ² synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN-Î³ and TNFÎ± may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.

Applications

Flow Cytometry, IF, WB, IHC-P

Recommander des dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivité

Human, Bovine, Canine, Chicken, Elk, Equine, Mouse, Porcine, Rabbit

Immunogène

Recombinant fragment corresponding to the C terminal core of bovine DCN.

Hôte

Mouse

Clonalité

Monoclonal

Clone

DCN/6289

Isotype

IgG1

Chaînes légères

lambda

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Decorin Antibody [DCN/6289] (A277635).

Synonymes

Bone proteoglycan II, CSCD, DCN, DCN protein, Decorin proteoglycan, Dermatan sulphate proteoglycans II, DKFZp686J19238, DSPG 2, DSPG2, PG 40, PG II, PG S2, PG-S2, PG40, PGII, PGS 2, PGS2, PGS2_HUMAN, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (2)

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Figure 1: Immunohistochemistry - Anti-Decorin Antibody [DCN/6289] - BSA and Azide free (A278223)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate tissue using Anti-Decorin Antibody [DCN/6289].

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Figure 2: Immunohistochemistry - Anti-Decorin Antibody [DCN/6289] - BSA and Azide free (A278223)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human placenta tissue using Anti-Decorin Antibody [DCN/6289] at 2µg/ml. Inset: PBS instead of the primary antibody. Secondary antibody negative control.