Recombinant Anti-Granzyme B Anticorps [rGZMB/4538] (A277892)

Anticorps monoclonal [rGZMB/4538] de souris contre Granzyme B pour WB et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Granzyme B Antibody [rGZMB/4538]
Description du produit
Recombinant mouse monoclonal [rGZMB/4538] antibody to Granzyme B.
Spécificité
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin s Disease.
Applications
WB, IHC-P
Recommander des dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 73-187, of human Granzyme B protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
rGZMB/4538
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
29-32 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Granzyme B Antibody [rGZMB/4538] - BSA and Azide free (A278480).
Synonymes
C11, Cathepsin G like 1, Cathepsin G-like 1, CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA-1, CTLA1, CTSGL1, Cytotoxic serine protease B, Cytotoxic T lymphocyte associated serine esterase 1, Cytotoxic T lymphocyte proteinase 2, Cytotoxic T-lymphocyte proteinase 2, Fragmentin 2, Fragmentin-2, GRAB_HUMAN, Granzyme 2, Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1), Granzyme-2, GranzymeB, GRB, Gzmb, Hlp, Human lymphocyte protein, Lymphocyte protease, Protease, serine, B, SECT, T cell serine protease 1-3E, T-cell serine protease 1-3E
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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