Anti-HOXB2 Anticorps [PCRP-HOXB2-1F2] (A278232)

Anticorps monoclonal [PCRP-HOXB2-1F2] de souris contre HOXB2 pour ELISA, IP, Flow Cytometry, IF, WB et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-HOXB2 Antibody [PCRP-HOXB2-1F2] - BSA and Azide free
Description du produit
Mouse monoclonal [PCRP-HOXB2-1F2] antibody to HOXB2.
Spécificité
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.
Applications
ELISA, IP, Flow Cytometry, IF, WB, IHC-P
Recommander des dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 114-220, of human HOXB2 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-HOXB2-1F2
Isotype
IgG2b
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
37.9 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-HOXB2 Antibody [PCRP-HOXB2-1F2] (A277644).
Synonymes
homeo box 2H, homeo box B2, homeobox B2, Homeobox protein Hox-2.8, Homeobox protein Hox-2H, Homeobox protein Hox-B2, Hox 2 8, Hox 2H, HOX2, HOX2H, HXB2_HUMAN, K8, K8 home protein
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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