Anti-IGFBP3 Anticorps [IGFBP3/3517] (A277661)

Anticorps monoclonal [IGFBP3/3517] de souris contre IGFBP3 pour Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-IGFBP3 Antibody [IGFBP3/3517]
Description du produit
Mouse monoclonal [IGFBP3/3517] antibody to IGFBP3.
Spécificité
The Insulin-like growth factor-binding proteins, or IGFBPs, are a family of homologous proteins that have co-evolved with the IGFs. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, as well as their concentration and distribution in the extracellular environment. In addition, the IGFBPs appear to have biological activity independent of the IGFs. Seven IGFBPs have thus far been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors. IGFBP3 is the most abundant IGFBP and is complexed with roughly 80% of the serum IGFs. Both IGFBP3 and IGFBP4 are released by dermal fibroblasts in response to incision injury.
Applications
Flow Cytometry, IF
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human IGFBP3 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
IGFBP3/3517
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
40 kDa / 44 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-IGFBP3 Antibody [IGFBP3/3517] - BSA and Azide free (A278249).
Synonymes
Acid stable subunit of the 140 K IGF complex, Binding protein 29, Binding protein 53, BP 53, BP53, Growth hormone dependent binding protein , IBP 3, IBP-3, IBP3, IBP3_HUMAN, IGF binding protein 3, IGF-binding protein 3, IGFBP 3, IGFBP-3, Insulin Like Growth Factor Binding Protein 3, Insulin-like growth factor binding protein 3 precursor, Insulin-like growth factor-binding protein 3
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Produits alternatifs à Anti-IGFBP3 Anticorps [IGFBP3/3517] (A277661)

Haut