Anti-Lipoprotein Lipase Anticorps [5D2] (Biotin) (A279433)

$420

Anticorps monoclonal [5D2] de souris contre Lipoprotein Lipase (Biotin) pour WB, IP et ELISA.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Lipoprotein Lipase Antibody [5D2] (Biotin)
Description du produit
Mouse monoclonal [5D2] antibody to Lipoprotein Lipase (Biotin).
Spécificité
This antibody recognises an epitope within amino acids 380-410 of lipoprotein lipase (LPL), a member of the AB hydrolase superfamily, which plays a pivotal role in lipoprotein metabolism and transport, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and the release of free fatty acids into peripheral tissues.A deficiency of LPL can result in hypertriglyceridemia, and LPL plays a critical role in the pathogenesis of atherosclerosis, and in particular the relationship between LPL and apolipoprotein E (ApoE), both of which are secreted in significant amounts by macrophages in developing arterial wall lesions. Mouse anti Lipoprotein lipase antibody, clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, and binds to LPL sequences involved in LPL, LPL receptor, and heparin interactions. Mouse anti Lipoprotein lipase antibody, clone 5D2 inhibits the activity of human LPL.
Applications
WB, IP, ELISA
Recommander des dilutions
ELISA: 1:50 - 1:200
Reactivité
Bovine, Rat, Human, Chicken, Guinea Pig
Réactivité croisée
This antibody does not cross react with Mouse
Immunogène
Purified bovine milk lipoprotein lipase.
Hôte
Mouse
Clonalité
Monoclonal
Clone
5D2
Isotype
IgG1
Conjuguer

Biotin

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
100 µg/ml
Masse moléculaire
Approximately 53 kDa using partially purified LPL from postheparin plasma.
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Notes générales
Mouse anti lipoprotein lipase antibody, clone 5D2 recognizes an epitope within amino acids 380-410 of lipoprotein lipase (LPL), a member of the AB hydrolase superfamily, which plays a pivotal role in lipoprotein metabolism and transport, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and the release of free fatty acids into peripheral tissues.A deficiency of LPL can result in hypertriglyceridemia, and LPL plays a critical role in the pathogenesis of atherosclerosis, and in particular the relationship between LPL and apolipoprotein E (ApoE), both of which are secreted in significant amounts by macrophages in developing arterial wall lesions. Mouse anti Lipoprotein lipase antibody, clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, and binds to LPL sequences involved in LPL, LPL receptor, and heparin interactions. Mouse anti Lipoprotein lipase antibody, clone 5D2 inhibits the activity of human LPL (Chang et al. 1998).
Synonymes
EC 3.1.1, EC 3.1.1.34, HDLCQ11, LIPD, LIPL_HUMAN, LPL, LPL protein, MGC137861
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.
Haut