Anti-MCM7 Anticorps [MCM7/1467] (A252481)

Anticorps monoclonal [MCM7/1467] de souris contre MCM7 pour Flow Cytometry, IF et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-MCM7 Antibody [MCM7/1467] - BSA and Azide free
Description du produit
Mouse monoclonal [MCM7/1467] antibody to MCM7.
Spécificité
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000 full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
Applications
Flow Cytometry, IF, IHC-P
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 195-319, of human MCM7 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MCM7/1467
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
88 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MCM7 Antibody [MCM7/1467] (A249301).
Synonymes
CDABP0042, CDC 47, CDC47, CDC47 homolog, Cdc47, S. cerevisiae, homolog of, DNA replication licensing factor MCM7, Homolog of S. cerevisiae Cdc47, MCM 2, MCM 7, MCM2, MCM2, formerly, MCM7 minichromosome maintenance deficient 7, MCM7_HUMAN, Minichromosome Maintainence 7, Minichromosome maintainence, S. cerevisiae, homolog of, Minichromosome maintenance complex component 7, Minichromosome maintenance deficient 7, Minichromosome maintenance protein 7, P1.1 MCM3, P1.1-MCM3, P1CDC47, P85MCM, PNAS 146, PNAS146, PPP1R104, Protein phosphatase 1, regulatory subunit 104
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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