Recombinant Anti-MUC16 Anticorps [OCA125/2349R] (A250627)

Name: Anti-MUC16 Antibody [OCA125/2349R]
Brand: Antibodies.com
SKU: A250627
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [OCA125/2349R] de lapin contre MUC16 pour IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

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Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Mots clés :

Anticorps Recombinant

Spécifications

Nom du produit

Anti-MUC16 Antibody [OCA125/2349R]

Description du produit

Recombinant rabbit monoclonal [OCA125/2349R] antibody to MUC16.

Spécificité

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

Applications

IHC-P

Recommander des dilutions

IHC-P: 1-2 µg/ml

Reactivité

Human

Immunogène

Purified human MUC16 protein.

Hôte

Rabbit

Clonalité

Monoclonal

Clone

OCA125/2349R

Isotype

IgG

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Masse moléculaire

>2,000 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC16 Antibody [OCA125/2349R] - BSA and Azide free (A253807).

Synonymes

CA 125, CA-125, CA125, CA125 ovarian cancer antigen, Cancer antigen 125, FLJ14303, MUC 16, MUC-16, MUC16_HUMAN, Mucin 16, Mucin 16 cell surface associated, Mucin-16, Mucin16, Ovarian cancer related tumor marker CA125, Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (3)

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Figure 1: Immunohistochemistry - Anti-MUC16 Antibody [OCA125/2349R] (A250627)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human ovarian carcinoma using Anti-MUC16 Antibody [OCA125/2349R].

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Figure 2: Immunohistochemistry - Anti-MUC16 Antibody [OCA125/2349R] (A250627)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human endometrial carcinoma using Anti-MUC16 Antibody [OCA125/2349R].

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Figure 3: SDS-PAGE - Anti-MUC16 Antibody [OCA125/2349R] (A250627)

SDS-PAGE analysis of Anti-MUC16 Antibody [OCA125/2349R] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.