Anti-NACC1 Anticorps [PCRP-NACC1-1A8] (A248213)

Anticorps monoclonal [PCRP-NACC1-1A8] de souris contre NACC1 pour Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-NACC1 Antibody [PCRP-NACC1-1A8]
Description du produit
Mouse monoclonal [PCRP-NACC1-1A8] antibody to NACC1.
Spécificité
The BTB (broad-complex, tramtrack and bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homo-oligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
Applications
Flow Cytometry
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells
Reactivité
Human
Immunogène
Recombinant full-length human NACC1 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-NACC1-1A8
Isotype
IgG2a
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
57 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NACC1 Antibody [PCRP-NACC1-1A8] - BSA and Azide free (A251396).
Synonymes
BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, FLJ37383, NAC-1, Nac1, NACC1_HUMAN, Nucleus accumbens-associated protein 1
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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