Anti-p63 Anticorps [PCRP-TP63-2G3] (A277835)

Anti-p63 Antibody [PCRP-TP63-2G3]

Mouse monoclonal [PCRP-TP63-2G3] antibody to p63.

p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length human p63 protein.

Mouse

Monoclonal

PCRP-TP63-2G3

IgG

Unconjugated

200 µg/ml

22 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-p63 Antibody [PCRP-TP63-2G3] - BSA and Azide free (A278423).

AIS, Amplified in squamous cell carcinoma, B(p51A), B(p51B), Chronic ulcerative stomatitis protein, CUSP, DN p63 alpha 1, DNp63, EEC3, id:ibd3516, Keratinocyte transcription factor, Keratinocyte transcription factor KET, KET, LMS, MGC115972, MGC192897, NBP, OFC8, OTTHUMP00000209732, OTTHUMP00000209733, OTTHUMP00000209734, OTTHUMP00000209735, OTTHUMP00000209737, OTTHUMP00000209738, OTTHUMP00000209739, OTTHUMP00000209740, OTTHUMP00000209741, OTTHUMP00000209742, OTTHUMP00000209743, OTTHUMP00000209744, p40, p51, P51/P63, p53-related protein p63, p53CP, P63_HUMAN, p73H, p73L, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73L, Transformation related protein 63, Transformation-related protein 63, Trp53rp1, Trp63, Tumor protein 63, Tumor protein p53-competing protein, Tumor protein p53-like, Tumor protein p63, Tumor protein p63 deltaN isoform delta, Tumor protein p73, Tumor protein p73-like