Anti-PAX8 Anticorps [PAX8/1491 + PAX8/1492] (A253542)

Anticorps Oligoclonal [PAX8/1491 + PAX8/1492] de souris contre PAX8 pour Flow Cytometry, IF, WB et IHC-P.

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Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-PAX8 Antibody [PAX8/1491 + PAX8/1492] - BSA and Azide free
Description du produit
Mouse monoclonal [PAX8/1491 + PAX8/1492] antibody to PAX8.
Spécificité
This antibody recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Applications
Flow Cytometry, IF, WB, IHC-P
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant human PAX8 protein.
Hôte
Mouse
Clonalité
Oligoclonal
Clone
PAX8/1491 + PAX8/1492
Isotype
IgG2a, kappa + IgG2b, kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
62 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

This oligoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-PAX8 Antibody [PAX8/1491 + PAX8/1492] (A250362).

Synonymes
OTTHUMP00000158659, OTTHUMP00000158660, OTTHUMP00000203723, OTTHUMP00000203724, Paired box 8, Paired box gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired box protein Pax-8, Paired domain gene 8, PAX 8, PAX8_HUMAN
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Produits alternatifs à Anti-PAX8 Anticorps [PAX8/1491 + PAX8/1492] (A253542)

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