Anti-PBX2 Anticorps [PCRP-PBX2-1C4] (A278321)

Anticorps monoclonal [PCRP-PBX2-1C4] de souris contre PBX2 pour ELISA, IP, Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-PBX2 Antibody [PCRP-PBX2-1C4] - BSA and Azide free
Description du produit
Mouse monoclonal [PCRP-PBX2-1C4] antibody to PBX2.
Spécificité
Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
Applications
ELISA, IP, Flow Cytometry, IF
Recommander des dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human PBX2 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-PBX2-1C4
Isotype
IgG2b
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
46 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-PBX2 Antibody [PCRP-PBX2-1C4] (A277733).
Synonymes
G17, Homeobox 12, Homeobox protein PBX2, HOX12, OTTHUMP00000029151, PBX2MHC, pre B cell leukemia homeobox 2, Pre-B-cell leukemia transcription factor 2, Protein G17
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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