beta 2 Defensin est un gène codé par le symbole DEFB4A. D'autres noms incluent: Beta-defensin 4A; Beta-defensin 2; BD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1; DEFB4A; DEFB102; DEFB2; DEFB4. beta 2 Defensin a une masse de 7.04kDa et une longueur d'acide aminé de 64.
Nous proposons 6 beta 2 Defensin kits ELISA pour la détection qualitative ou quantitative de beta 2 Defensin à partir d'échantillons Humain, Souris et Bovin.
Informations sur les Gènes et les Protéines
Résumé UniProt
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036).
Résumé Entrez
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.
Spécificité tissulaire
Expressed in the skin and respiratory tract.
Similitudes de séquence
Belongs to the beta-defensin family. LAP/TAP subfamily.
Localisation cellulaire
Secreted.
