beta Defensin 3 est un gène codé par le symbole DEFB103A. D'autres noms incluent: Beta-defensin 103; Beta-defensin 3; BD-3; Defensin, beta 103; Defensin-like protein; DEFB103A; BD3; DEFB103; DEFB3. beta Defensin 3 a une masse de 7.7kDa et une longueur d'acide aminé de 67.
Nous proposons 7 beta Defensin 3 kits ELISA pour la détection qualitative ou quantitative de beta Defensin 3 à partir d'échantillons Humain, Souris et Bovin.
Informations sur les Gènes et les Protéines
Résumé UniProt
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.
Résumé Entrez
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans.
Spécificité tissulaire
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
Similitudes de séquence
Belongs to the beta-defensin family.
Localisation cellulaire
Secreted.
