CXCR1 est un gène codé par le symbole CXCR1. D'autres noms incluent: C-X-C chemokine receptor type 1; CXC-R1; CDw128a; High affinity interleukin-8 receptor A; IL-8R A; IL-8 receptor type 1; CMKAR1; IL8RA. CXCR1 a une masse de 39.79kDa et une longueur d'acide aminé de 350.
Nous proposons 6 CXCR1 kits ELISA pour la détection qualitative ou quantitative de CXCR1 à partir d'échantillons Humain, Souris, Rat et Lapin.
Informations sur les Gènes et les Protéines
Résumé UniProt
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Résumé Entrez
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Similitudes de séquence
Belongs to the G-protein coupled receptor 1 family.
Localisation cellulaire
Cell membrane.
