Eotaxin 3 est un gène codé par le symbole CCL26. D'autres noms incluent: C-C motif chemokine 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; CCL26; SCYA26. Eotaxin 3 a une masse de 10.65kDa et une longueur d'acide aminé de 94.
Nous proposons 3 Eotaxin 3 kits ELISA pour la détection qualitative ou quantitative de Eotaxin 3 à partir d'échantillons Humain.
Informations sur les Gènes et les Protéines
Résumé UniProt
Chemoattractant for eosinophils and basophils (PubMed:10415065, PubMed:10488147). Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils (PubMed:10415065, PubMed:10488147, PubMed:11425309).
Résumé Entrez
This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases.
Spécificité tissulaire
Ubiquitously expressed at low levels in various tissues including heart and ovary.
Similitudes de séquence
Belongs to the intercrine beta (chemokine CC) family.
Localisation cellulaire
Secreted.
