Fatty Acid Synthase est un gène codé par le symbole FASN. D'autres noms incluent: FASN; FAS. Fatty Acid Synthase a une masse de 273.43kDa et une longueur d'acide aminé de 2511.
Nous proposons 10 Fatty Acid Synthase kits ELISA pour la détection qualitative ou quantitative de Fatty Acid Synthase à partir d'échantillons Humain, Souris, Rat, Lapin et Poulet.
Informations sur les Gènes et les Protéines
Résumé UniProt
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.
Résumé Entrez
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Spécificité tissulaire
Ubiquitous. Prominent expression in brain, lung, and liver.
Localisation cellulaire
Cytoplasm. Melanosome.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
