GPA33 est un gène codé par le symbole GPA33. Communément appelé aussi: Cell surface A33 antigen; Glycoprotein A33. GPA33 a une masse de 35.63kDa et une longueur d'acide aminé de 319.
Nous proposons 3 GPA33 kits ELISA pour la détection qualitative ou quantitative de GPA33 à partir d'échantillons Humain et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
May play a role in cell-cell recognition and signaling.
Résumé Entrez
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
Spécificité tissulaire
Expressed in normal gastrointestinal epithelium and in 95% of colon cancers.
Modification post-traductionnelle
N-glycosylated, contains approximately 8 kDa of N-linked carbohydrate.
Localisation cellulaire
Membrane.
