HPR est un gène codé par le symbole HPR. Il est également connu sous le nom de Haptoglobin-related protein. HPR a une masse de 39.03kDa et une longueur d'acide aminé de 348.
Nous proposons 3 HPR kits ELISA pour la détection qualitative ou quantitative de HPR à partir d'échantillons Humain.
Informations sur les Gènes et les Protéines
Résumé UniProt
Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.
Spécificité tissulaire
In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell lines.
Similitudes de séquence
Belongs to the peptidase S1 family.
Localisation cellulaire
Secreted.
Secreted into blood plasma and associated with subtypes of high density lipoproteins (HDL).
