ICAM1 est un gène codé par le symbole ICAM1. Communément appelé aussi: Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor. ICAM1 a une masse de 57.83kDa et une longueur d'acide aminé de 532.
Nous proposons 21 ICAM1 kits ELISA pour la détection qualitative ou quantitative de ICAM1 à partir d'échantillons Humain, Souris, Rat, Porcin, Lapin et Canin.
Informations sur les Gènes et les Protéines
Résumé UniProt
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Résumé Entrez
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Similitudes de séquence
Belongs to the immunoglobulin superfamily. ICAM family.
Modification post-traductionnelle
Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
Localisation cellulaire
Membrane.
