Nestin est un gène codé par le symbole NES. Il est également connu sous le nom de NES. Nestin a une masse de 177.44kDa et une longueur d'acide aminé de 1621.
Nous proposons 7 Nestin kits ELISA pour la détection qualitative ou quantitative de Nestin à partir d'échantillons Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).
Résumé Entrez
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
Spécificité tissulaire
CNS stem cells.
Similitudes de séquence
Belongs to the intermediate filament family.
Modification post-traductionnelle
Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized (By similarity).
