Carbonic Anhydrase I est un gène codé par le symbole CA1. D'autres noms incluent: Carbonic anhydrase 1; Carbonate dehydratase I; Carbonic anhydrase B; CAB; CA-I; CA1. Carbonic Anhydrase I a une masse de 28.87kDa et une longueur d'acide aminé de 261.
Nous proposons 7 des anticorps contre Carbonic Anhydrase I, élevé dans Lapin et Chèvre, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
Résumé Entrez
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Similitudes de séquence
Belongs to the alpha-carbonic anhydrase family.
Localisation cellulaire
Cytoplasm.
