CD23 est un gène codé par le symbole FCER2. D'autres noms incluent: Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; FCER2A; CLEC4J; FCE2; IGEBF. CD23 a une masse de 36.47kDa et une longueur d'acide aminé de 321.
Nous proposons 52 des anticorps contre CD23, élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF et Cytométrie en Flux avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Résumé Entrez
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Modification post-traductionnelle
N- and O-glycosylated.
Localisation cellulaire
Cell membrane. Cell membrane. Secreted.
Also exists as a soluble excreted form, sCD23.
