hCG beta est un gène codé par le symbole CGB3. Communément appelé aussi: Choriogonadotropin subunit beta 3; Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotropin chain beta; CGB3; CGB. hCG beta a une masse de 17.74kDa et une longueur d'acide aminé de 165.
Nous proposons 43 des anticorps contre hCG beta, élevé dans Lapin, Souris et Sheep, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF, IP et RIA avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Résumé Entrez
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
Spécificité tissulaire
High expression in the placenta throughout pregnancy.
Similitudes de séquence
Belongs to the glycoprotein hormones subunit beta family.
Localisation cellulaire
Secreted.
