ITGA11 est un gène codé par le symbole ITGA11. Il est également connu sous le nom de Integrin alpha-11. ITGA11 a une masse de 133.47kDa et une longueur d'acide aminé de 1188.
Nous proposons 3 des anticorps contre ITGA11, élevé dans Lapin et Chèvre, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain et Souris.
Informations sur les Gènes et les Protéines
Résumé UniProt
Integrin alpha-11/beta-1 is a receptor for collagen.
Résumé Entrez
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.
Spécificité tissulaire
According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver.
Similitudes de séquence
Belongs to the integrin alpha chain family.
Localisation cellulaire
Membrane.
