Neuron navigator 1 est un gène codé par le symbole NAV1. Communément appelé aussi: Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1; NAV1; KIAA1151; KIAA1213; POMFIL3; STEERIN1. Neuron navigator 1 a une masse de 202.47kDa et une longueur d'acide aminé de 1877.
Nous proposons 4 des anticorps contre Neuron navigator 1, élevé dans Rat, qui sont appropriés pour le WB et ICC/IF avec des échantillons dérivés de Humain.
Informations sur les Gènes et les Protéines
Résumé UniProt
May be involved in neuronal migration.
Résumé Entrez
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.
Spécificité tissulaire
Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.
Similitudes de séquence
Belongs to the Nav/unc-53 family.
Localisation cellulaire
Cytoplasm > Cytoskeleton.
Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity).
