Noelin est un gène codé par le symbole OLFM1. Communément appelé aussi: Neuronal olfactomedin-related ER localized protein; Olfactomedin-1; OLFM1; NOE1; NOEL1. Noelin a une masse de 55.34kDa et une longueur d'acide aminé de 485.
Nous proposons 11 des anticorps contre Noelin, élevé dans Lapin, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli (By similarity).
Résumé Entrez
This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.
Localisation cellulaire
Secreted. Cell junction > Synapse. Endoplasmic reticulum. Cell projection > Axon. Perikaryon.
