RhD est un gène codé par le symbole RHD. Il est également connu sous le nom de: Blood group Rh(D) polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen. RhD a une masse de 45.21kDa et une longueur d'acide aminé de 417.
Nous proposons 6 des anticorps contre RhD, élevé dans Lapin, qui sont appropriés pour le WB et ELISA avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Résumé Entrez
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.
Spécificité tissulaire
Restricted to tissues or cell lines expressing erythroid characters.
Similitudes de séquence
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Modification post-traductionnelle
Palmitoylated.
Localisation cellulaire
Cell membrane.
