Sec24C est un gène codé par le symbole SEC24C. Il est également connu sous le nom de: Protein transport protein SEC24-related protein C; KIAA0079. Sec24C a une masse de 118.33kDa et une longueur d'acide aminé de 1094.
Nous proposons 5 des anticorps contre Sec24C, élevé dans Lapin, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF et IP avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:10214955, PubMed:17499046, PubMed:18843296, PubMed:20427317). Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317). May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296).
Résumé Entrez
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified.
Spécificité tissulaire
Ubiquitous.
Similitudes de séquence
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
Localisation cellulaire
Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum membrane. Cytoplasm > Cytosol.
