SLC10A1 est un gène codé par le symbole SLC10A1. Il est également connu sous le nom de: Sodium/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; NTCP. SLC10A1 a une masse de 38.12kDa et une longueur d'acide aminé de 349.
Nous proposons 3 des anticorps contre SLC10A1, élevé dans Lapin, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain.
Informations sur les Gènes et les Protéines
Résumé UniProt
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
Résumé Entrez
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.
Similitudes de séquence
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Localisation cellulaire
Membrane.
