SLC16A3 est un gène codé par le symbole SLC16A3. Il est également connu sous le nom de: Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 3; MCT4. SLC16A3 a une masse de 49.47kDa et une longueur d'acide aminé de 465.
Nous proposons 2 des anticorps contre SLC16A3, élevé dans Lapin, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Résumé Entrez
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998
Spécificité tissulaire
Highly expressed in skeletal muscle.
Similitudes de séquence
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Localisation cellulaire
Cell membrane.
