SPACA3 est un gène codé par le symbole SPACA3. Il est également connu sous le nom de: Sperm acrosome membrane-associated protein 3; Cancer/testis antigen 54; CT54; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; Lysozyme-like protein 3; Sperm lysozyme-like protein 1; Sperm protein reactive with antisperm antibodies; Sperm protein reactive with ASA; LYC3; LYZL3; SLLP1; SPRASA. SPACA3 a une masse de 23.43kDa et une longueur d'acide aminé de 215.
Nous proposons 14 des anticorps contre SPACA3, élevé dans Lapin, qui sont appropriés pour le WB, IHC, ELISA et IP avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
Résumé Entrez
The protein encoded by this gene is a sperm surface protein that may be involved in adhesion to the egg prior to fertilization. While the encoded protein has significant similarity to lysozyme at the amino acid level, it has no detectable bacteriocidal activity. Several transcript variants encoding different isoforms have been found for this gene.
Spécificité tissulaire
The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
Similitudes de séquence
Belongs to the glycosyl hydrolase 22 family.
Modification post-traductionnelle
The processed form derives from the membrane form by proteolytic processing.
Localisation cellulaire
Cytoplasmic vesicle > Secretory vesicle > Acrosome membrane.
Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction.
