CD2 est un gène codé par le symbole CD2. D'autres noms incluent: T-cell surface antigen Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; SRBC. CD2 a une masse de 39.45kDa et une longueur d'acide aminé de 351.
Nous proposons 5 CD2 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Résumé Entrez
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene.
Localisation cellulaire
Cell membrane.
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