CD23 est un gène codé par le symbole FCER2. D'autres noms incluent: Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; FCER2A; CLEC4J; FCE2; IGEBF. CD23 a une masse de 36.47kDa et une longueur d'acide aminé de 321.
Nous proposons 1 CD23 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Résumé Entrez
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Modification post-traductionnelle
N- and O-glycosylated.
Localisation cellulaire
Cell membrane. Cell membrane. Secreted.
Also exists as a soluble excreted form, sCD23.
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