CD34 est un gène codé par le symbole CD34. Il est également connu sous le nom de Hematopoietic progenitor cell antigen CD34. CD34 a une masse de 40.72kDa et une longueur d'acide aminé de 385.
Nous proposons 4 CD34 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Résumé Entrez
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.
Spécificité tissulaire
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
Similitudes de séquence
Belongs to the CD34 family.
Modification post-traductionnelle
Highly glycosylated.
Localisation cellulaire
Membrane.
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