CD5 est un gène codé par le symbole CD5. D'autres noms incluent: T-cell surface glycoprotein Lymphocyte antigen T1/Leu-1; LEU1. CD5 a une masse de 54.58kDa et une longueur d'acide aminé de 495.
Nous proposons 2 CD5 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
May act as a receptor in regulating T-cell proliferation.
Résumé Entrez
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Modification post-traductionnelle
Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.
Localisation cellulaire
Cell membrane.
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