CD93 est un gène codé par le symbole CD93. D'autres noms incluent: Complement component C1q receptor; C1q/MBL/SPA receptor; C1qR; CDw93; Complement component 1 q subcomponent receptor 1; Matrix-remodeling-associated protein 4; C1QR1; MXRA4. CD93 a une masse de 68.56kDa et une longueur d'acide aminé de 652.
Nous proposons 6 CD93 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Résumé Entrez
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
Spécificité tissulaire
Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin.
Modification post-traductionnelle
N- and O-glycosylated.
Localisation cellulaire
Membrane.
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