LFA3 est un gène codé par le symbole CD58. Communément appelé aussi: Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58. LFA3 a une masse de 28.15kDa et une longueur d'acide aminé de 250.
Nous proposons 2 LFA3 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Résumé Entrez
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
Localisation cellulaire
Cell membrane.
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