Transglutaminase 2 est un gène codé par le symbole TGM2. Il est également connu sous le nom de: Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; TG(C); Transglutaminase H; TGase H; Transglutaminase-2; TGase-2; TGM2. Transglutaminase 2 a une masse de 77.33kDa et une longueur d'acide aminé de 687.
Nous proposons 3 Transglutaminase 2 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Catalyzes the cross-linking of proteins, such as WDR54, and the conjugation of polyamines to proteins.
Résumé Entrez
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Similitudes de séquence
Belongs to the transglutaminase superfamily. Transglutaminase family.
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